Table of contents
- What is Xiaflex Injection?
- What drug does Xiaflex contains?
- How does Xiaflex work?
- Xiaflex treament cycle & Risks associated with it
- Side Effects of Xiaflex Injection
- Precautions & Warnings
- Drug Interactions
- Xiaflex cost
- How is Xiaflex administered?
- Xiaflex commercial bent carrot
- Xiaflex review
- Frequently Asked Questions
What is Xiaflex Injection?
Xiaflex Injection is a prescription medication used to treat various conditions, including Dupuytren’s contracture and Peyronie’s disease. It is the only FDA-approved medication for the treatment of Peyronie’s disease.
Xiaflex is an injectable medicine composed of collagenase clostridium histolyticum, an enzyme that breaks down collagen. To be more specific, Xiaflex contains two different types of purified collagenase clostridium histolyticum (AUX-I and AUX-II).
Xiaflex injections are administered directly into the affected area, which helps break down the collagen formed into lumps or bands.
This helps to relieve pain and restore flexibility in the affected area. The injections are typically given over several visits and may be repeated as needed. Patients should talk to their doctor to determine if the Xiaflex injection is the right treatment option.
To date, many people have benefited from Xiaflex injections. However, it is an expensive treatment but guarantees the results.
Read – How does Xiaflex work for Peyronie’s disease?
What drug does Xiaflex contains?
Xiaflex is a prescription medication used to treat conditions where excessive scar tissue is formed. Xiaflex contains the active ingredient collagenase clostridium histolyticum, a type of enzyme that breaks down scar tissue effectively.
Collagenase clostridium histolyticum is a mixture of a group of enzymes obtained from the bacteria named C. histolyticum. In 2010, it was approved by the FDA for the treatment of Peyronie’s and Dupuytren’s diseases.
Read – Xiaflex Before and After Peyronie’s Disease Treatment
How does Xiaflex work?
Xiaflex is a prescription medicine used to treat Peyronie’s disease, a condition in which the penis becomes bent and can’t be straightened.
The medicine comes in a vial and can be injected directly into the affected area. It breaks down the collagen causing the contracture and allowing the penis to be straightened. The injection is usually given in a doctor’s clinic, which may take about 15-25 minutes.
After the injection, the patient is usually required to perform a straightening exercise which the performing doctor will do. It is advised for the patient to avoid sexual activity for at least the next two days. The process is repeated almost 2-3 times and usually takes two to four weeks before the patient can see any results.
Read – What is Xiaflex? What is Xiaflex used for?
Xiaflex treament cycle & Risks associated with it
- Risk of having penile hematoma, ecchymoses, swelling, and pain at the site of administration should be openly discussed between Doctors and patients.
- It should be injected only in the scar tissue; any contact with the urethra, nerves, blood vessels, corpora cavernosa, or other collagen-containing structures of the penis can cause severe side effects.
- Xiaflex injections are only recommended when the curvature is more than 30 degrees and stopped when the curvature comes below 15 degrees.
- Also, note that the product’s safety after four cycles is not known or studied well. So, talk to your doctor to know more about this.
Xiaflex treatment consists of a maximum of four cycles, taking approximately 24 weeks for complete treatment. Each Xiaflex cycle takes about 6 weeks, depending on your response and recovery.
Side Effects of Xiaflex Injection
Xiaflex treats certain conditions, such as Peyronie’s disease and Dupuytren’s contracture. While the injection can effectively treat these conditions, it is important to be aware of some potential side effects.
Common side effects include swelling, redness, pain at the injection site, and bruising and tenderness. Less common side effects may include infection, nerve injury, and an allergic reaction.
If you experience any of these side effects, it is important to contact your doctor immediately. It is also important to note that Xiaflex can interact with certain medications, so it is important to tell your doctor about any other medications you are taking.
Precautions & Warnings
Xiaflex is an injectable medication used to treat Peyronie’s disease, which is a condition that causes the penis to curl. This medication comprises highly concentrated collagenase, which breaks down collagen fibres in the tissue causing the contracture.
While Xiaflex can be an effective treatment for Peyronie’s disease, taking certain precautions and being aware of the potential side effects is important.
It would be best to tell your doctor or pharmacist about allergies before using collagenase or other similar enzymes. It may contain inactive ingredients that may cause allergic reactions. Please consult your doctor for more information.
It is advised to avoid the use of any traction or straightening devices while taking via flex injections treatment.
Drug Interactions
As with any medication, there are potential drug interactions with Xiaflex that must be taken into consideration before using it.
Common drug interactions include:
Anticoagulants – Clopidogrel, Prasugrel, Ticagrelor, Aspirin
NSAIDs – Acetaminophen, Ibuprofen, Etoricoxib, Aceclofenac
Patients should also be aware of any over-the-counter medications, as these can interact with Xiaflex and increase the risk of side effects.
It is important to consult your healthcare provider before taking any medication to ensure no potential drug interactions.
Xiaflex cost
The cost of xiaflex is about $6,191.08 per dose. The usual treatment cycle requires two injections per month, which amounts to a total cost of $12382.16 per cycle. Usually, it takes three to four such cycles for complete relief from the Peyronie’s disease.
Xiaflex can be taken at discounted price of $1,200 under Copay Assistance Program . However, this price will vary depending on where you live and how much it costs in your area.
Read – Xiaflex success rate for Peyronie’s Disease
Why is Xiaflex so expensive?
Xiaflex is an injectable medication used to treat Dupuytren’s contracture and Peyronie’s disease, which affects the connective tissue of the palm and penis.
The cost of Xiaflex is quite high, ranging from $5,500 to $6,191.08 per injection. The high cost is due to several factors, including the cost of research and development and the limited availability of the drug.
Additionally, Xiaflex is a patented medication and must be administered by a healthcare professional, which results in additional costs for the patient.
is Xiaflex covered by medicare?
Xiaflex is not classified under medication, so Medicare does not cover the full cost of Xiaflex. However, it covers about 80% of the cost, and you will be required to pay the remaining 20% of the cost.
It is important to check with your insurance provider to see what coverage they offer. Additionally, some patients may be eligible for patient assistance programs from some of the insurance companies covering Xiaflex, which can help reduce medication costs.
Read – How long does Xiaflex stay in your system?
How is Xiaflex administered?
It is administered through a series of injections directly into the affected tissue. The injections are typically given in intervals of at least two days.
Xiaflex treatment usually takes three to four weeks. The injections are usually given in two sets, two weeks apart.
The medication is administered as an injection directly into the affected area. The injection is typically done by a specialist or doctor, who will first numb the area with a local anaesthetic.
Once the area is numb, the doctor will inject the Xiaflex injection into the affected area. After the injection, the doctor will usually apply a splint to make the penis straight.
The process usually takes about 30 minutes, and most patients report minimal discomfort.
Xiaflex commercial bent carrot
Xiaflex review
Xiaflex is a prescription medication injected directly into the scar tissue of Peyronie’s disease, which helps to release the curvature and restore the full function of the penis gradually.
Reviews of Xiaflex have been overwhelmingly positive, with many patients reporting significant improvements in the curvature after just one or two cycles.
The treatment is generally safe and well-tolerated, although some patients may experience mild side effects such as bruising or swelling at the injection site. Overall, Xiaflex is a safe and effective treatment for Peyronie’s disease without any side effects.
Read – Xiaflex before & after picture
Frequently Asked Questions
Xiaflex is an injection having collagenase clostridium histolyticum as an active ingredient. It is the only available FDA approved medication used to treat Peyronie’s disease.
It is a biological enzyme derived from Clostridium histolyticum, Xiaflex works by breaking down the scar tissue that cause the curvature. The medication is injected directly into the affected area, which causes the scar tissue to break down and the affected fingers to straighten.
Xiaflex is typically injected directly into the affected area and starts its action immediately after you take effect. After that, Xiaflex will remain in your system for about 30 – 45 minutes. Although Xiaflex is not completely cleared from your body, it might not be detected in the blood after 30 minutes.
After receiving Xiaflex, many people notice an immediate breakdown of in their condition. The injection itself may cause pain and swell at the injection site, which typically subsides within a few days. Many people also experience bruising and swelling in the injected area, which can last for a day or more.
The XIAFLEX® injection is a patented medication approved by the Food and Drug Administration (FDA) for use in Peyronie’s disease. In a clinical trial of over 10 patients, Xiaflex was found to reduce the curvature of the penis within three to four cycles.
Usually, people taking Xiaflex recovers within two days of its administration. people are asked to avoid any sexual activity involving penis in those two days.
The cost of xiaflex is about $6,191.08 per dose. The usual treatment cycle requires two injections per month, which amounts to a total cost of $12382.16 per cycle. Usually, it takes three to four such cycles for complete relief from the Peyronie’s disease.
Xiaflex is approved by FDA to treat Dupuytren’s contracture and Peyronie’s disease.
Xiaflex is expensive because it is a patented treatment for Peyronie’s disease and has no alternative.
Xiaflex is a prescription medication approved by the FDA to treat Peyronie’s disease. Drugs work by breaking down fibrous tissue in the penis that causes the condition. Studies have shown that Xiaflex effectively reduces the curvature and scar tissue formed on the penis.
Xiaflex treatment is a non-invasive procedure that can treat Peyronie’s disease. In most cases, the treatment is not painful; your doctor also numbs the area before injecting it.
According to a clinical study, Xiaflex is 96.2% effective in improving curvature. it is also a is safe, effective, and cost efficient treatment for the Peyronie’s disease approved by FDA.
No, there is no generic version of Xiaflex currently available. Xiaflex is a patented medication used to treat Dupuytren’s contracture and Peyronie’s disease. The FDA has not yet approved generic versions of the drug. However, there have been reports of a generic version of Xiaflex becoming available shortly. This likely leads to a decrease in the cost of the medication.
Xiaflex is a brand of collagenase injection used to treat Dupuytren’s Contracture and Peyronie’s disease. Xiaflex is owned by Endo International pl and manufactured by Asahi Kasei Pharma in Japan. Xiaflex was approved by the U.S. Food and Drug Administration in 2010 and is currently the only FDA-approved treatment for Dupuytren’s Contracture & Peyronie’s disease.
You can drive if you are taking it for Peyronie’s disease, although it is not recommended but if you don’t have any discomfort then go on. In case of Dupuytren’s contracture it may cause trouble while driving. talk to your doctor about driving a vehicle after taking Xiaflex.
